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Molecular Interaction Data

At the heart of the Cell Blueprint lies the DeepLife Human Interactome, a meticulously curated multi-omics interaction network. Unlike other cellular networks, DeepLife’s interactome prioritizes interactions based on quality, directionality, and directness. Notably, it distinguishes between directed interactions, elucidating effector-affected relationships, and direct interactions, bypassing intermediary molecules. This meticulous curation ensures the integrity of the network, paving the way for more accurate analyses of cellular processes.

Statistics

The Cell Blueprint boasts an impressive array of molecular data, encompassing:

  • A comprehensive repository comprising 16,274 protein-coding genes, 964 miRNAs, and 81 lncRNAs.
  • A vast network comprising 192,274 interactions, with 164,765 characterised as direct and directed. These interactions span diverse modalities, including post-translational, transcriptional, and post-transcriptional interactions mediated by miRNAs and lncRNAs.
  • Multiple Data Sources: Curated from over 100 databases, including reputable sources such as BioGRID and Reactome, helping ensure the robustness and reliability of the network.